Exploring the mysterious East Wing in Resident Evil Requiem brings survival horror fans face to face with several intricate brainteasers. Among the most notable challenges is the puzzle box located inside the Lead Researcher's Office, which holds key items needed for main story progression. Unlocking this container requires gathering clues from around the room and securing a specific key item to bypass a physical barrier first.
Bypassing the Heavy Padlock
Before you can interact with the puzzle box dials, you will notice that a heavy padlock secures the chest. Regular inventory tools cannot break this lock, requiring players to retrieve a bottle of Corrosive from the nearby Conference Room. Once acquired, apply the liquid directly to the padlock to melt the metal and access the combination mechanism.
Finding the Hidden Symbol Clues
Solving the combination naturally requires inspecting framed photographs scattered around the office space. Looking closely at the backgrounds of these photos reveals four distinct celestial symbols. By analyzing the image order on the desk and surrounding tables, players can piece together the proper sequence without relying on blind guesswork.
The Puzzle Box Combination and Solution
To open the box directly, input the sequence Star, Sun, Moon, and Sun into the mechanism. Each symbol corresponds to the celestial themes depicted throughout the care center's documentation. Entering the four symbols correctly unlocks the container immediately, granting access to the key items stored within.
Rewards Obtained From the Office Container
Opening the puzzle box rewards players with the Sun Quartz, which serves as a crucial key item for unlocking the Central Hall door. Additionally, players receive a leatherbound notebook containing instructions to solve the organ transport box puzzle later in the facility. These items ensure smooth progression through the remaining hazards of the East Wing.